Triglyceride-to-HDL-cholesterol Ratio as a Measure of Insulin Resistance in Obese Children and Adolescents

Abstract

Childhood obesity is closely linked to insulin resistance, type 2 diabetes, and metabolic syndrome. [1] [2] Traditional methods of assessing insulin resistance, such as the hyperinsulinemic-euglycemic clamp, are precise but impractical for routine clinical use in pediatric populations. [3] This study evaluates the triglyceride-to-HDL-cholesterol (TG/HDL) ratio as an alternative, simple and effective marker of insulin resistance in obese children and adolescents.